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14.02.2018 |

Mathematics explains why Crispr-Cas9 sometimes cuts the wrong DNA

Initially the Crispr-Cas9 system seemed to be accurate, but it is now apparent that it sometimes also cuts non-target DNA sequences

Once again we find more honesty about the imprecision of the CRISPR gene editing system in the medical research field, as with the new paper featured below, than in the field of crop biotechnology.

1. Mathematics explains why Crispr-Cas9 sometimes cuts the wrong DNA

2. Hybridization kinetics explains CRISPR-Cas off-targeting rules

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